Do, T., et al.,
60(2), 147-150,
Protein Expression and Purification,
2008
Determining the dynamic binding capacity of resins is an essential step in optimization of a purification process. The authors describe an approach based on the use of Octet systems to compare the dynamic binding capacity of three protein A resins for a recombinant chimeric antibody. The method can be modified for quantification of any protein for which a specific capture molecule is available.
Read More