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高效细胞清洗,可最大化减少细胞损失并提供理想的检测性能

AquaMax® 微孔板洗板机是一个独立的系统,可配置用于 96 和 384 孔微孔板。既可使用预先设置好的清洗、浸泡和吸液程序,又可使用简便的触摸屏界面来创建个性化的多步骤洗板程序。对于生化检测,该洗板机可去除未结合的物质和未反应的试剂。对于细胞水平测定,该洗板机可提供 96 或 384 孔专业的细胞清洗头,给予脆弱的贴壁细胞温和的清洗。

  • 易于使用 图标

    易于安装

    AquaMax 洗板机的运行不需要外部泵和电脑,缩减了实验台占地面积。可更换的清洗头在几秒钟内即可安装完成,无需工具、校准或对齐。

  • 准确度 图标

    无需进行孔板设置

    在所有孔中同时进行 96 和 384 孔吸液和分液,从而实现高精度检测和更快的微孔板处理,无需进行孔板设置或象限处理。

  • 高效 图标

    运行多个清洗方案

    用不同颜色标记的两个或者四个洗液接口,与不同洗瓶的管子相匹配,方便缓冲液瓶和洗液瓶的快速连接,允许同时运行多个清洗程序, 而无需切换不同类型的洗瓶。

AquaMax 微孔板洗板机

AquaMax 微孔板洗板机

特点

  • 易于使用 图标

    轻松操作

    按下按钮即可启动清洗程序,轻松完成 96 孔和 384 孔微孔板的洗板。Standby 选项可使仪器处于待机准备状态,针头浸在缓冲液中可以随时启动。

  • 高效 图标

    便利性

    精确的分液和吸液控制,确保在不破坏细胞的情况下进行处理。快速、连续以及底部清洗设置可最大限度地缩短清洗时间。

  • 灵活性 图标

    灵活性

    通过轻松更换 96 和 384 清洗头和仪器自动探测清洗头,可轻松配置 AquaMax 洗板机,以满足当前和后续高精度的微孔板应用需求。

  • 自动化 图标

    自动化

    该款洗板机可与最新的自动化工作站轻松整合。它与 Molecular Devices StakMax® 微孔板堆板机和许多机械手臂处理器兼容。

经验证的 GxP 解决方案可确保数据完整性和合规性

我们为 GMP/GLP 实验室提供一整套经过验证的合规性解决方案,可以帮助您快速、自信地建立合规实验室。

  • 一流的微孔板读板机和洗板机可支持您的所有实验需求
  • IQ/OQ/PM 服务以数字化和合规格式保存仪器记录
  • 软件安装服务可验证并记录所需的组件是否按操作规范安装
  • 软件验证服务支持美国食品药品监督管理局 (FDA) 21 CFR Part 11 指南
  • 采用可追溯的验证板来检验您的微孔板读板机性能,帮助您得到可靠结果
适用于 GMP-GLP 实验室的 GxP 合规性解决方案

 

AquaMax 微孔读板机(酶标仪)的应用

AquaMax 微孔板洗板机的技术参数和可选配置

AquaMax 微孔板洗板机的相关资源

报告内容
视频和网络研讨会
抗原/免疫原发现和优化

免疫学和疫苗开发工作流程

AquaMax 微孔板洗板机

AquaMax 微孔板洗板机

  • Citation
    Dated: Dec 01, 2017
    Publication Name: Muscle Stem Cells

    Systematic Identification of Genes Regulating Muscle Stem Cell Self-Renewal and Differentiation

    The hallmark of stem cells is their capability to either self-renew or to differentiate into a different cell type. Adult skeletal muscle contains a resident muscle stem cell population (MuSCs) known as satellite cells, which enables regeneration of damaged muscle tissue throughout most of adult life. During skeletal muscle regeneration, few MuSCs… View more

    The hallmark of stem cells is their capability to either self-renew or to differentiate into a different cell type. Adult skeletal muscle contains a resident muscle stem cell population (MuSCs) known as satellite cells, which enables regeneration of damaged muscle tissue throughout most of adult life. During skeletal muscle regeneration, few MuSCs self-renew to maintain the muscle stem cell pool while others expand rapidly and subsequently undergo myogenic differentiation to form new myofibers. However, like for other stem cell types, the molecular networks that govern self-renewal and/or differentiation of MuSCs remain largely elusive. We recently reported a method to isolate sufficient amounts of purified MuSCs from skeletal muscle which enables us to study their cell autonomous properties. Here, we describe a lentiviral, image-based loss-of function screening pipeline on primary MuSCs that enables systematic identification of genes that regulate muscle stem cell function.

    Contributors: Krishnamoorthy Sreenivasan, Thomas Braun, Johnny Kim  
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  • Citation
    Dated: Feb 15, 2017
    Publication Name: Nature

    Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

    A highly protective malaria vaccine would greatly facilitate the prevention and elimination of malaria and containment of drug-resistant parasites1. A high level (more than 90%) of protection against malaria in humans has previously been achieved only by immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (PfSPZ)… View more

    A highly protective malaria vaccine would greatly facilitate the prevention and elimination of malaria and containment of drug-resistant parasites1. A high level (more than 90%) of protection against malaria in humans has previously been achieved only by immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (PfSPZ) inoculated by mosquitoes2,3,4; by intravenous injection of aseptic, purified, radiation-attenuated, cryopreserved PfSPZ (‘PfSPZ Vaccine’)5,6; or by infectious PfSPZ inoculated by mosquitoes to volunteers taking chloroquine7,8,9,10 or mefloquine11 (chemoprophylaxis with sporozoites). We assessed immunization by direct venous inoculation of aseptic, purified, cryopreserved, non-irradiated PfSPZ (‘PfSPZ Challenge’12,13) to malaria-naive, healthy adult volunteers taking chloroquine for antimalarial chemoprophylaxis (vaccine approach denoted as PfSPZ-CVac)14. Three doses of 5.12 × 104 PfSPZ of PfSPZ Challenge12,13 at 28-day intervals were well tolerated and safe, and prevented infection in 9 out of 9 (100%) volunteers who underwent controlled human malaria infection ten weeks after the last dose (group III). Protective efficacy was dependent on dose and regimen. Immunization with 3.2 × 103 (group I) or 1.28 × 104 (group II) PfSPZ protected 3 out of 9 (33%) or 6 out of 9 (67%) volunteers, respectively. Three doses of 5.12 × 104 PfSPZ at five-day intervals protected 5 out of 8 (63%) volunteers. The frequency of Pf-specific polyfunctional CD4 memory T cells was associated with protection. On a 7,455 peptide Pf proteome array, immune sera from at least 5 out of 9 group III vaccinees recognized each of 22 proteins. PfSPZ-CVac is a highly efficacious vaccine candidate; when we are able to optimize the immunization regimen (dose, interval between doses, and drug partner), this vaccine could be used for combination mass drug administration and a mass vaccination program approach to eliminate malaria from geographically defined areas.

    Contributors: Benjamin Mordmüller, Güzin Surat, Heimo Lagler, Sumana Chakravarty, Andrew S. Ishizuka, Albert Lalremruata, Markus Gmeiner, Joseph J. Campo, Meral Esen, Adam J. Ruben, Jana Held, Carlos Lamsfus Calle, Juliana B. Mengue, Tamirat Gebru, Javier Ibáñez, Mihály Sulyok, Eric R. James, Peter F. Billingsley, KC Natasha, Anita Manoj, Tooba Murshedkar, Anusha Gunasekera, Abraham G. Eappen, Tao Li, Richard E. Stafford, Minglin Li, Phil L. Felgner, Robert A. Seder, Thomas L. Richie, B. Kim Lee Sim, Stephen L. Hoffman & Peter G. Kremsner -Show fewer authors  
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  • Citation
    Dated: Nov 01, 2014
    Publication Name: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

    Evaluation of yolk protein levels as estrogenic biomarker in bivalves; comparison of the alkali-labile phosphate method (ALP) and a species-specific immunoassay (ELISA)

    Altered concentration of the vertebrate yolk protein precursor vitellogenin is a recognized biomarker for endocrine disruption in fish, and within recent years yolk protein alteration has also been associated with endocrine disruption in bivalves. Species-specific, direct and sensitive methods for quantification of vitellogenin in fish have been… View more

    Altered concentration of the vertebrate yolk protein precursor vitellogenin is a recognized biomarker for endocrine disruption in fish, and within recent years yolk protein alteration has also been associated with endocrine disruption in bivalves. Species-specific, direct and sensitive methods for quantification of vitellogenin in fish have been available for years whereas bivalve yolk protein levels have been estimated indirectly by alkali-labile phosphate (ALP) liberated from high molecular weight proteins because the sequence and biochemical structure of most bivalve yolk proteins are unknown. By applying a species-specific enzyme-linked immunosorbent assay (ELISA) for accurate determination of yolk protein level the impact of 17β-estradiol (57, 164 and 512 ng/L) on the freshwater bivalve Unio tumidus was investigated and compared with ALP estimations. Seven weeks of exposure during the pre-spawning and spawning period had no consistent effect on yolk protein concentration in hemolymph, and ALP levels in hemolymph also remained unchanged in both males and females. Further, basal male and female ALP levels were indistinguishable whereas the ELISA demonstrated that yolk protein levels of females exceeded male levels at the time of sampling, although male basal levels were high compared to fish. Altogether it is shown that individual ALP levels do not reflect yolk protein levels and hence hemolymph ALP levels cannot serve as biomarker for estrogenic exposure during the pre-spawning and spawning period in U. tumidus. The necessity of sensitive and validated biomarkers for reliable interpretation of data and the utility of ALP and yolk protein levels as biomarkers in bivalves are discussed.

    Contributors: Jane E. Morthorst, Henrik Holbech, Morten Jeppesen, Karin L. Kinnberg, Knud L. Pedersen, Poul Bjerregaard  
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AquaMax® 微孔板洗板机

产品

产品编号:

AquaMax 2K 套装包括 AquaMax 2000 微孔板洗板机, 96 板清洗头, 2 个带液位传感器的检测瓶, 和带传感器的 10L 废液瓶
AQUAMAX 2K
AquaMax 4K 套装包括 AquaMax 4000 微孔板洗板机, 96 板清洗头, 4 个带液位传感器的检测瓶, 和带传感器的 10L 废液瓶 AQUAMAX 4K
StakMax 堆板机
STAKMAX
AquaMax 消毒剂
R8156
AquaMax 2000 洗板机的现场合规性保证 IQOQ 服务(安装认证/操作认证服务,包括系统所有者认证记录的详细 IQOQ 结果)
AQ2000-IQOQSVC-OS
AquaMax 4000 洗板机的现场合规性保证 IQOQ 服务(安装认证/操作认证服务,包括系统所有者认证记录的详细 IQOQ 结果)
AQ4000-IQOQSVC-OS

AquaMax 微孔板洗板机的相关产品和服务