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预置的实验模板和定制的检测工作流程可简化微孔板数据的采集和分析

兼容 Windows 10 的 SoftMax® Pro 软件提供简捷、灵活的数据分析模式,它预置即时可行的实验程序、分析算法和 21 种不同的曲线拟合选项。软件既能够对 Molecular Devices 微孔板读板机读取的数据优化,也能够对其他来源导入的数据进行优化,简化分析步骤并生成报告。合规性工具可为受监管实验室提供监管依据。

  • 简化数据获取 图标

    简化数据获取

    该软件有多种实验检测的选择方式,可选择预设的实验方案(内含采集数据的设置),也可自定义设置实验参数进行数据采集。

  • 导入和分析复杂数据 图标

    导入和分析复杂数据

    导入从其它科研仪器中采集到的微孔板格式原始数据,整合来自不同数据源的数据,并通过数据一致性评估方法来减少误差。

  • 轻松发表专业文章 图标

    轻松发表专业文章

    该软件提供灵活的数据输出格式,用于发表报告。可在实验室电脑中查看数据、将数据保存为 PDF 文件、导出到 Excel 文件或 XML 中,或者导入实验室信息管理系统 (LIMS) 。

SoftMax Pro 7 软件

SoftMax Pro 7 软件

特点

  • 内置模板 图标

    内置模板

    提供超过 160 种方案(包括适用于我们仪器的整套试剂、SpectraTest® 验证板和适配器的实验步骤)和预设的检测参数来进行各种常规检测。

  • 先进的读板机(酶标仪)控制流程方式 图标

    先进的读板机(酶标仪)控制流程方式

    支持建立自定义检测工作流程,运行多任务动力学检测,支持非连续动力学检测来暂停和继续动力学读数。

  • 灵活计算 图标

    灵活计算

    提供数据分析功能,例如 21 种不同曲线拟合选项、简化不同孔板分析和计算,自动计算相对活性、EC50 和 Z 因子等。

  • 轻松进行项目管理 图标

    轻松进行项目管理

    在一个模板中对多个孔板读数进行分组。在备注部分显示结果、条件性通过/失败说明、内置图表以及图像,以便轻松预览全部结果。

  • 安全保存的电子记录 图标

    安全保存的电子记录

    通过细化的权限结构和唯一的登录名提供受控制用户的访问权限,并支持电子签名和审计追踪,验证,授权和批准。

  • 验证工具降低成本 图标

    验证工具降低成本

    与使用多套工具来收集和分析数据相比,一套完整的微孔板读板机(酶标仪)验证工具套件可将验证成本和时间减少 50%。

经验证的 GxP 解决方案可确保数据完整性和合规性

我们为 GMP/GLP 实验室提供一整套经过验证的合规性解决方案,可以帮助您快速、自信地建立合规实验室。

  • 一流的微孔板读板机和洗板机可支持您的所有实验需求
  • IQ/OQ/PM 服务以数字化和合规格式保存仪器记录
  • 软件安装服务可验证并记录所需的组件是否按操作规范安装
  • 软件验证服务支持美国食品药品监督管理局 (FDA) 21 CFR Part 11 指南
  • 采用可追溯的验证板来检验您的微孔板读板机性能,帮助您得到可靠结果
适用于 GMP-GLP 实验室的 GxP 合规性解决方案

 

SoftMax Pro 软件的应用

SoftMax Pro 软件的技术参数和可选配置

 

温馨提示:

  • 为了防止数据丢失,请关闭硬盘、CPU 和 USB 接口的所有睡眠和休眠设置
  • 禁用 Windows 自动更新
  • 在软件不使用仪器时,手动更新 Windows;这些选项可在 Windows 控制面板中启用

注:不再支持在 Windows XP 操作系统上安装和使用 SoftMax Pro 软件。软件未在 Windows XP 上测试或验证。

SoftMax Pro 软件的资源

报告内容
视频和网络研讨会
第 5 周视频略缩图

微孔板读板机的都市神话:读取-复制-粘贴-分析。重复...... 听起来很熟悉?

第 4 周视频略缩图

微孔板读板机的都市神话:超越基础 - 实时、分辨时间和转移能量

第 3 周视频略缩图

微孔板读板机的都市神话:“优化?但手册上说达到 490 nm 我就应该高兴了!”

 第 1 周视频略缩图

微孔板读板机的都市神话:OD、RFU 或 RLU - 它们究竟是什么,还有为什么越大并不总是越好!

第 2 周视频略缩图

微孔板读板机的都市神话:哪一款微孔板读板机?决策很重要,以及如何减少困惑!

SoftMax Pro 7 软件

在 SoftMax Pro 7 软件中使用导出功能

SoftMax Pro 6.4.1 导入功能

SoftMax Pro 6.4.1 导入功能

SoftMax Pro 6.5 采集视图

SoftMax Pro 6.5 采集视图

使用 SoftMax Pro 7 工作流程编辑器创建多任务动力学检测工作流程

使用 SoftMax Pro 7 工作流程编辑器创建一个多任务动力学检测工作流程

SoftMax Pro 7 软件

SoftMax Pro 7 软件

在 SoftMax Pro 7 软件中创建新图表

在 SoftMax Pro 7 软件中创建一个新图表

在 SoftMax Pro 7 中修改现有图表

在 SoftMax Pro 7 软件中修改现有图表

在 SoftMax Pro 7 中建立一个板模板

在 SoftMax Pro 7 软件中建立一个板模板

SoftMax Pro 7 中的自动存储选项

使用 SoftMax Pro 7 软件中的自动存储选项

SoftMax Pro 7 软件中的吸光度检测

在 SoftMax Pro 7 软件中设置一次吸光度检测

曲线拟合功能和 PLA

曲线拟合特征和 PLA:SoftMax Pro 6 实用指南

SoftMax Pro 6 软件

SoftMax Pro 6 软件

使用 SoftMax Pro 6 软件进行微孔板数据采集和数据分析

如何使用 SoftMax Pro 6 软件进行微孔板数据采集和数据分析

SoftMax Pro 6 软件入门指南

SoftMax Pro 6 软件入门指南

SoftMax Pro 6 数据采集提示和技巧

SoftMax Pro 6 数据采集提示和技巧

SoftMax Pro 6 数据采集提示和技巧(法语版)

SoftMax Pro 6 数据采集提示和技巧(法语版)

SoftMax Pro 6 数据采集提示和技巧(德语版)

SoftMax Pro 6 数据采集提示和技巧(德语版)

Softmax Pro 6.2 GxP:易于兼容

Softmax Pro 6.2 GxP:易于兼容

在 SoftMax Pro 7 软件中建立一个稀释的板模板

在 SoftMax Pro 7 软件中建立一个稀释的板模板

  • Citation
    Dated: Apr 23, 2021
    Publication Name: Nature Protocols

    Quantification of SARS-CoV-2 neutralizing antibody by wild-type plaque reduction neutralization, microneutralization and pseudotyped virus neutralization assays

    Virus neutralization assays measure neutralizing antibodies in serum and plasma, and the plaque reduction neutralization test (PRNT) is considered the gold standard for measuring levels of these antibodies for many viral diseases. We have developed procedures for the standard PRNT, microneutralization assay (MNA) and pseudotyped virus… View more

    Virus neutralization assays measure neutralizing antibodies in serum and plasma, and the plaque reduction neutralization test (PRNT) is considered the gold standard for measuring levels of these antibodies for many viral diseases. We have developed procedures for the standard PRNT, microneutralization assay (MNA) and pseudotyped virus neutralization assay (PNA) for severe acute respiratory syndrome coronavirus 2. The MNA offers advantages over the PRNT by reducing assay time, allowing increased throughput and reducing operator workload while remaining dependent upon the use of wild-type virus. This ensures that all severe acute respiratory syndrome coronavirus 2 antigens are present, but Biosafety Level 3 facilities are required. In addition to the advantages of MNA, PNA can be performed with lower biocontainment (Biosafety Level 2 facilities) and allows for further increases in throughput. For each new vaccine, it is critical to ensure good correlation of the neutralizing activity measured using PNA against the PRNT or MNA. These assays have been used in the development and licensure of the ChAdOx1 nCoV-19 (AstraZeneca; Oxford University) and Ad26.COV2.S (Janssen) coronavirus disease 2019 vaccines and are critical for demonstrating bioequivalence of future vaccines.

    Contributors: Kevin R. Bewley, Naomi S. Coombes, Luc Gagnon, Lorna McInroy, Natalie Baker, Imam Shaik, Julien R. St-Jean, Natalie St-Amant, Karen R. Buttigieg, Holly E. Humphries, Kerry J. Godwin, Emily Brunt, Lauren Allen, Stephanie Leung, Phillip J. Brown, Elizabeth J. Penn, Kelly Thomas, Greg Kulnis, Bassam Hallis, Miles Carroll, Simon Funnell & Sue Charlton  
    Go to article

  • Citation
    Dated: Dec 15, 2020
    Publication Name: Vaccine

    Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

    Enzyme linked immunosorbent assay (ELISA) has been widely used to measure antibody titers for evaluating the immunogenicity of a vaccine. However, there is as yet no generally accepted way of expressing the ELISA results in the case of experimental vaccines, since there is usually no uniform standard. Both end point and single dilution methods… View more

    Enzyme linked immunosorbent assay (ELISA) has been widely used to measure antibody titers for evaluating the immunogenicity of a vaccine. However, there is as yet no generally accepted way of expressing the ELISA results in the case of experimental vaccines, since there is usually no uniform standard. Both end point and single dilution methods have significant disadvantages. In this paper, we obtained reproducible data with fewer dilutions of samples by addition of serially diluted standard serum to each ELISA plate. Since this ELISA method gives reliable antibody titer with less labor than other methods, it can strongly support vaccine development.

    Contributors: Kazutoyo Miura, Andrew C. Orcutt, Olga V.Muratova, Louis H.Miller Allan, Saul, Carole A. Long  
    Go to article

  • Citation
    Dated: Aug 17, 2020
    Publication Name: Springer

    Drug Removal Strategies in Competitive Ligand Binding Neutralizing Antibody (NAb) Assays: Highly Drug-Tolerant Methods and Interpreting Immunogenicity Data

    Neutralizing anti-drug antibody (NAb) assays often have lower drug tolerance (DT) than trough drug concentrations, potentially under-estimating NAb incidence. To improve DT, drug-specific proteins were coupled to magnetic beads to deplete drug in the sample. View more

    Neutralizing anti-drug antibody (NAb) assays often have lower drug tolerance (DT) than trough drug concentrations, potentially under-estimating NAb incidence. To improve DT, drug-specific proteins were coupled to magnetic beads to deplete drug in the sample.

    Contributors: Michael A. Partridge, Elif Kabuloglu Karayusuf, Gary Shyu, Camille Georgaros, Albert Torri & Giane Sumner  
    Go to article

  • Citation
    Dated: Mar 03, 2020
    Publication Name: International Immunopharmacology

    Parallel comparison of three methodologies for measuring functional C1-inhibitor in Hereditary angioedema patients

    Hereditary angioedema (HAE) types I and II are characterized by functional C1 inhibitor (fC1-INH) deficiency which results in bradykinin overproduction. Sensitive, specific and robust methods to quantitate fC1-INH in human samples are required for diagnosing HAE and/or to measure pharmacodynamic activity of C1-INH drugs in clinical studies. View more

    Hereditary angioedema (HAE) types I and II are characterized by functional C1 inhibitor (fC1-INH) deficiency which results in bradykinin overproduction. Sensitive, specific and robust methods to quantitate fC1-INH in human samples are required for diagnosing HAE and/or to measure pharmacodynamic activity of C1-INH drugs in clinical studies.

    Contributors: Archana Kapoor, Brijesh K. Garg, Zhiwei Zhou, Peng Lu, Priya S.Chockalingam  
    Go to article

  • Citation
    Dated: Jun 17, 2019
    Publication Name: Nature

    Mitotically heritable effects of BMAA on striatal neural stem cell proliferation and differentiation

    The widespread environmental contaminant β-methylamino-L-alanine (BMAA) is a developmental neurotoxicant that can induce long-term learning and memory deficits. Studies have shown high transplacental transfer of 3H-BMAA and a significant uptake in fetal brain. View more

    The widespread environmental contaminant β-methylamino-L-alanine (BMAA) is a developmental neurotoxicant that can induce long-term learning and memory deficits. Studies have shown high transplacental transfer of 3H-BMAA and a significant uptake in fetal brain.

    Contributors: Paula Pierozan & Oskar Karlsson  
    Go to article

  • Citation
    Dated: Oct 01, 2018
    Publication Name: Crop Protection

    Identification and characterization of abamectin resistance in Tetranychus urticae Koch populations from greenhouses in Turkey

    The two-spotted spider mite, Tetranychus urticae Koch is one of the most serious pests in greenhouses and has developed high resistance to many classes of acaricides rapidly. Three T. urticae populations were collected from vegetable greenhouses in Antalya and Muğla, Turkey. These populations showed high resistance levels to abamectin ranging… View more

    The two-spotted spider mite, Tetranychus urticae Koch is one of the most serious pests in greenhouses and has developed high resistance to many classes of acaricides rapidly. Three T. urticae populations were collected from vegetable greenhouses in Antalya and Muğla, Turkey. These populations showed high resistance levels to abamectin ranging between 223 and 404 fold compared to a susceptible population. The interaction of some synergists (piperonyl butoxide; PBO, diethyl maleate; DEM and S-benzyl O,O-diisopropyl phosphorothioate; IBP) with abamectin was analyzed showing possible implication of esterases in resistances in the three populations studied. The activities of esterase, glutathione S-transferase (GST) and cytochrome P450 (p450) was determined using α-naphthyl acetate, 1-chloro-2,4 dinitrobenzene (CDNB) and 7-ethoxycoumarin (7-EC) as substrates, respectively. In all field populations, esterase, glutathione S-transferase and P450 activities were higher, when compared to the susceptible population (GSS). The presence of known abamectin resistance target site mutations (G314D and G326E) on the glutamate gated chloride channels was also examined. However, no target site–resistance mutation was detected in all three populations. According to our results, detoxification enzymes, but no target site intensivity seem to play role in abamectin resistance in field T. urticae populations from Turkey.

    Contributors: Naciye Sena Çağatay, Pauline Menault, Maria Riga, John Vontas, Recep Ay  
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  • Citation
    Dated: Apr 04, 2001
    Publication Name: Journal of Investigative Dermatology

    An Alternative Approach to Depigmentation by Soybean Extracts via Inhibition of the PAR-2 Pathway

    The protease-activated receptor 2, expressed on keratinocytes but not on melanocytes, has been ascribed functional importance in the regulation of pigmentation by phagocytosis of melanosomes. Inhibition of protease-activated receptor 2 activation by synthetic serine protease inhibitors requires keratinocyte-melanocyte contact and results in… View more

    The protease-activated receptor 2, expressed on keratinocytes but not on melanocytes, has been ascribed functional importance in the regulation of pigmentation by phagocytosis of melanosomes. Inhibition of protease-activated receptor 2 activation by synthetic serine protease inhibitors requires keratinocyte-melanocyte contact and results in depigmentation of the dark skinned Yucatan swine, suggesting a new class of depigmenting mechanism and agents. We therefore examined natural agents that could exert their effect via the protease-activated receptor 2 pathway. Here we show that soymilk and the soybean-derived serine protease inhibitors soybean trypsin inhibitor and Bowman-Birk inhibitor inhibit protease-activated receptor 2 cleavage, affect cytoskeletal and cell surface organization, and reduce keratinocyte phagocytosis. The depigmenting activity of these agents and their capability to prevent ultraviolet-induced pigmentation are demonstrated both in vitro and in vivo. These results imply that inhibition of the protease-activated receptor 2 pathway by soymilk may be used as a natural alternative to skin lightening.

    Contributors: Christine Paine, Elizabeth Sharlow, Frank Liebel, Magdalena Eisinger, StanleyShapiro, MiriSeiberg  
    Go to article

SoftMax Pro 7 软件

产品

年度订阅许可

未过期许可证

SoftMax Pro 标准软件

兼容 Windows 10

订阅一年的最新版 SoftMax Pro 7。包含一个激活密钥, 一年后到期。每年更新。

部件号:
SMP7 PROF SUBSCR

 

为经验证的学术机构提供特价。
如需获取我们的 SoftMax Pro 学术优惠,请联系您所在当地的销售代表或拨打 1 (877) 589-2214 下单。

如需查看美国以外的联系电话, 请访问我们的联系方式页面

最新版 SoftMax Pro 7 的未过期许可证。 包括四个激活密钥。

部件号:SMP7 PROF 

 

为经验证的学术机构提供特价。
如需获取我们的 SoftMax Pro 学术优惠,请联系您所在当地的销售代表或拨打 1 (877) 589-2214 下单。

如需查看美国以外的联系电话, 请访问我们的联系方式页面

SoftMax Pro Importer XLS

要求 SoftMax Pro 6.4.1 或更高版本

订阅 1 年便可将数据从 Excel 模板导入 SoftMax Pro。

包含一个激活密钥, 一年后到期。每年更新。

部件号:(点击下方以购买/下载)
SMP.IMPORT.XLS

 

SoftMax Pro Importer XLS 和 XML

要求 SoftMax Pro 6.4.1 或更高版本

订阅 1 年便可将数据从 Excel 模板或 XML 文件导入 SoftMax Pro。

包含一个激活密钥, 一年后到期。每年更新。

零件号:(点击下方以购买/下载)
SMP.IMPORT.XLS.AND.XML

未过期许可证允许将数据从 Excel 模板或 XML 文件导入 SoftMax Pro。

包括为每台电脑提供的一个激活密钥。

部件号:(单击下方购买/下载)SMP.IMPORT.XLS.AND.XML.NONEXP
 

SoftMax Pro 软件的相关产品和服务